Animals which are cloned are genetically identical and transgenic refers to an organism having DNA from two or more organisms.
Commercial production of antibodies (example using transgenic cows):
- We want to obtain an egg cell from the cow, and from a human we will take a cell and we are going to remove using restriction enzymes we are going to cut a gene associated with antibody production.
- In the egg cell we knock out the cow antibody gene and then we are going to add the human gene using ligase enzyme.
- The cow cell is then developed by mitosis to form clone of cells - an embryo.
- This is transferred to a surrogate mother which will then produce genetically identical calves and in this particular example, the gene for antibodies is expressed and the human antibodies are collected from the milk of the animal in a large commercial scale.