Thursday, 3 November 2011

2.74 ADH

Describe the role of ADH (antidiuretic  hormone) in regulating the water content of the blood.
  • Anti-diuretic hormone is produced in a region of the brain known as the hypothalamus. Like all hormones it flows through the blood stream and the target is the kidney.
  • The effect of ADH is to control and alter the composition of water which is in blood.
  • ADH has the ability to make blood more or less concentrated to keep the tissue fluid isotonic.
  • This is the role of ADH.
  • ADH targets the collecting duct and the effect of ADH is that it allows more water to come out of the collecting duct
  • We know that water selective reabsorption happens in the collecting duct but ADH can increase the amount of water going into the blood.
  • ADH makes the collecting duct walls more porous so that more water can escape from the collecting duct and this water goes back to the blood. 
  • The consequence of ADH secretion is that the urine would be more concentrated and have a lower volume.

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